Human PSG6/PSG10 Recombinant Protein (RPES3944)

(No reviews yet) Write a Review
SKU:
RPES3944
Product Type:
Recombinant Protein
Species:
Human

Description

system_update_altDatasheet

Human PSG6/PSG10 Recombinant Protein

PSG6 is a pregnancy-specific glycoprotein(PSG). PSGs are secreted proteins which are produced by the rodent and primate placenta and play a critical role in pregnancy success. The levels of PSGs are highest during the third trimester of pregnancy, a time marked by the most profound suppression of MS disease attacks. PSGs regulate T-cell function. The regulation of T-cell function during pregnancy is likely the result of significant hormonal changes and may well involve immunoregulatory proteins derived from the placenta. Pregnancy specific glycoproteins (PSGs) are the most abundant placentally derived glycoproteins in the maternal serum. PSG1, PSG6, PSG6N, and PSG11 induce dose-dependent secretion of anti-inflammatory cytokines by human monocytes. Human and murine PSGs exhibit cross-species activity.

Product Name:Human PSG6/PSG10 Recombinant Protein (RPES3944)
Product Code:RPES3944
Size:20µg
Species:Human
Expressed Host:Baculovirus-Insect Cells
Synonyms:CGM3,PSBG-10,PSBG-12,PSBG-6,PSG10,PSG12,PSG6,PSGGB
Accession:NP_001027020
Sequence:Met 1-His 424
Fusion tag:C-His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:A DNA sequence encoding the human PSG6 (Met 1-His 424) (NP_001027020) was expressed, with a C-terminal polyhistidine tag.
Purity:> 87 % as determined by reducing SDS-PAGE.
Mol Mass:45.2 kDa
AP Mol Mass:58 kDa
Formulation:Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 7.4
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
View AllClose

0 Reviews

View AllClose

Related Products