Human PSA/KLK3 Recombinant Protein (RPES2968)
- SKU:
- RPES2968
- Product Type:
- Recombinant Protein
- Species:
- Human
Description
system_update_altDatasheet
Human PSA/KLK3 Recombinant Protein
KLK3; also known as APS; is short for Prostate-specific antigen. It is a 261 aa. protein which belongs to the peptidase S1 family and Kallikrein subfamily. This protein has 5 isforms produced by alternative splicing. It is a secreted protein and can forms a heterodimer with SERPINA5 which can inhibit its activity. KLK3 is also strongly inhibited by Zn2+; 100 times more abundant in semen than in serum. This inhibition is relieved by exposure to semenogelins; which are avid zinc binders. KLK3 can hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum.
| Product Name: | Human PSA/KLK3 Recombinant Protein (RPES2968) |
| Product Code: | RPES2968 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | APS,Hk3,KLK2A1,PSA,Prostate-Specific Antigen, PSA, Gamma-Seminoprotein, Seminin, Kallikrein-3, P-30 Antigen, Semenogelase, |
| Accession: | P07288 |
| Sequence: | Ile25-Pro261 |
| Fusion tag: | C-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Kallikrein-3/Prostate-specific antigen is produced by our Mammalian expression system and the target gene encoding Ile25-Pro261 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 27.1 kDa |
| AP Mol Mass: | 35 kDa |
| Formulation: | Supplied as a 0.2 µm filtered solution of 20mM TrisHcl; 150mM NaCl;1mM CaCl2;pH7.5. |
| Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt; store it immediately at<-20°C. |
| Stability and Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
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