Epigenetics & Nuclear Signaling Recombinant Proteins
Human Protamine-2/PRM2 Recombinant Protein (RPES3025)
- SKU:
- RPES3025
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Epigenetics & Nuclear Signaling
Description
Human Protamine-2/PRM2 Recombinant Protein
RRM2 is one of two non-identical ribonucleotide reductase subunits. RRM2 is responsible formation of deoxyribonucleotides from ribonucleotides. The encoded protein (M2) is generated via a cell-cycle-dependent process. RRM2 transcription can start from two different promoters, resulting in two isoforms with different N-termini lengths. It's also been observed on chromosomes 1 and X that RRM2 pseudogenes have been identified. Choriocarcinoma and Diamond-Blackfan Anemia 20 are two diseases related to RRM2. Pyrimidine metabolism and E2F-mediated DNA replication regulation are two related pathways to RRM2. Human Protamine-2/PRM2 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
| Product Name: | Human Protamine-2/PRM2 Recombinant Protein (RPES3025) |
| Product Code: | RPES3025 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | Ribonucleoside-Diphosphate Reductase Subunit M2, Ribonucleotide Reductase Small Chain, Ribonucleotide Reductase Small Subunit, RRM2, RR2 |
| Accession: | P31350 |
| Sequence: | Met 1-Phe389 |
| Fusion tag: | C-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Ribonucleotide Reductase Small Chain is produced by our Mammalian expression system and the target gene encoding Met1-Phe389 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 45.9 kDa |
| AP Mol Mass: | 47 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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