Epigenetics & Nuclear Signaling Recombinant Proteins

Human PPIase/PPIL1 Recombinant Protein (RPES1550)

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SKU:
RPES1550
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Epigenetics & Nuclear Signaling

Description

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Human PPIase/PPIL1 Recombinant Protein

Peptidyl-Prolyl Cis-Trans Isomerase-Like 1 (PPIase) belongs to the cyclophilin-type PPIase family. PPIases can accelerate the folding of proteins and catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIase is a ubiquitous protein and has highly expression in heart ;skeletal and muscle. PPIase contains a PPIase cyclophilin-type domain and four Cyclosporin A binding regions. PPIase might play an important role in proliferation of cancer cells through modulation of phosphorylation of stathmin. It is suggested that PPIase can act as as a novel molecular target for colon-cancer therapy.

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