Human PMEL ELISA Kit

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SKU:
HUFI01867
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P40967
Sensitivity:
0.094ng/ml
Range:
0.156-10ng/ml
ELISA Type:
Sandwich
Synonyms:
PMEL, P100, P1, Melanoma-associated ME20 antigen, Melanocytes lineage-specific antigen GP100, Silver locus protein homolog, Premelanosome protein, ME20-M, ME20M, Melanocyte protein Pmel 17, PMEL17, SILV
Reactivity:
Human
Research Area:
Metabolism

Description

Human PMEL ELISA Kit

PMEL encodes a melanocyte-specific type I transmembrane glycoprotein, which is enriched in melanosomes. PMEL plays an essential role in the structural organization of premelanosomes, by generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. PMEL may be used as a melanoma-specific serum marker, and is also implicated in increasing susceptibility to diseases such as vitiligo and congenital melanocytic nevus.

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