Human platelet membrane glycoRecombinant Protein IV/CD36/SR-B3 Fc Chimera Recombinant Protein (Fc Tag)

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SKU:
RPES6168
Product Type:
Recombinant Protein
Species:
Human

Description

Product Name:Human platelet membrane glycoRecombinant Protein IV/CD36/SR-B3 Fc Chimera Recombinant Protein (Fc Tag)
Product Code:RPES6168
Size:10µg
Species:Human
Expression Host:HEK293 Cells
Synonyms:Fatty acid translocase, Glycoprotein IIIb, FATCHDS7, Leukocyte differentiation antigen CD36, PAS IV, Platelet collagen receptor, SCARB3, Thrombospondin receptor, CD36
Mol Mass:73.8 kDa
AP Mol Mass:90-130 kDa
Tag:C-Fc
Purity:> 90 % as determined by reducing SDS-PAGE.
Endotoxin Level:< 1.0 EU per μg of the protein as determined by the LAL method.
Bio Activity:Testing in progress
Sequence:Gly30-Asn439
Accession:P16671
Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Formulation:Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution:Please refer to the printed manual for detailed information.
Background:Platelet Glycoprotein 4 (CD36) is an integral membrane glycoprotein that has multiple physiological functions. It is broadly expressed on a variety of cell types including microvascular endothelium, adipocytes, skeletal muscle, epithelial cells of the retina, breast, and intestine, smooth muscle cells, erythroid precursors, platelets, megakaryocytes, dendritic cells, monocytes/macrophages, and microglia. As a member of the scavenger receptor family, CD36 is a multiligand pattern recognition receptor that interacts with a large number of structurally dissimilar ligands, including long chain fatty acid (LCFA), advanced glycation end products (AGE), thrombospondin-1,oxidized lowdensity lipoproteins (oxLDLs), high density lipoprotein (HDL), phosphatidylserine, apoptotic cells, β amyloid fibrils (fAβ), collagens I and IV, and Plasmodium falciparuminfected erythrocytes. CD36 is required for the antiangiogenic effects of thrombospondin-1 in the corneal neovascularization assay. It plays a role in lipid metabolism and has been identified as a fatty acid translocase necessary for the binding and transport of LCFA in cells and tissues.
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