Human cytomegalovirus (HCMV) GlycoRecombinant Protein B / gB Recombinant Protein (ECD, Fc Tag) (RPES6970)

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SKU:
RPES6970
Product Type:
Recombinant Protein
Species:
Virus
Application Area:
Research Tool Proteins
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Description

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Product Name:Human cytomegalovirus (HCMV) GlycoRecombinant Protein B / gB Recombinant Protein (ECD, Fc Tag)
Product Code:RPES6970
Size:100µg
Species:CMV
Expression Host:HEK293 Cells
Mol Mass:104kDa
AP Mol Mass:135-145 kDa
Tag:C-hFc
Purity:> 80 % as determined by reducing SDS-PAGE.
Endotoxin Level:< 1.0 EU per μg of the protein as determined by the LAL method.
Bio Activity:Testing in progress
Sequence:Met 1-Lys 700
Accession:AAA45920.1
Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Formulation:Lyophilized from sterile PBS, pH 7.4 Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution:Please refer to the printed manual for detailed information.
Background:Cytomegalovirus (CMV) (human herpesvirus 5) glycoprotein B, also referred as CMV gB or gB, which belongs to the herpesviridae glycoprotein B family. It is a 97-amino acid glycoprotein encoded by the ORF of UL55. Cytomegalovirus Glycoprotein B protein is the most abundant component of the envelope, a target of neutralizing antibodies with at least two defined neutralizing epitopes and an essential replication component. Cytomegalovirus Glycoprotein B protein plays important roles in HCMV entry, cell-cell spread of internal virions, and fusion of infected cells. In addition, Cytomegalovirus Glycoprotein B protein is one envelope protein capable of heparin binding. It forms a physical association with host cell annexin II independent of the presence of calcium.
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