Human PD-L1 / CD274 ELISA Kit

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SKU:
HUFI02708
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
Q9NZQ7
Sensitivity:
3.75pg/ml
Range:
6.25-400pg/ml
ELISA Type:
Sandwich
Synonyms:
PDCD1LG1, CD274, PDCD1L1, PDCD1LG1, PD-L1, B7-H, B7-H1, B7H1, CD274 antigen, CD274 molecule, B7 homolog 1, PDL1, PDCD1 ligand 1, programmed cell death 1 ligand 1, Programmed death ligand 1
Reactivity:
Human
Research Area:
Immunology

Description

Human PD-L1 / CD274 ELISA

CD274 (CD274 Molecule) protein is also known as Programmed Cell Death 1 Ligand (PD-L1), which is a member of the B7 family of proteins. CD274 is a ligand for the PD-1 receptor, which is expressed on T cells. When PD-L1 binds to PD-1, it inhibits T cell activation and proliferation. CD274 is expressed on a variety of cells, including activated T cells, B cells, dendritic cells, macrophages, and some tumor cells. The expression of CD274 on tumor cells can limit the effectiveness of anti-tumor immunity by suppressing T cell activation and proliferation.

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