Growth Factors & Cytokines Recombinant Proteins
Human OSTF1 Recombinant Protein (RPPB0828)
- SKU:
- RPPB0828
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q92882
- Research Area:
- Growth Factors & Cytokines
Description
| Product Name: | Human OSTF1 Recombinant Protein |
| Product Code: | RPPB0828 |
| Size: | 50µg |
| Species: | Human |
| Target: | OSTF1 |
| Synonyms: | SH3P2, OSF, OSTF-1, Osteoclast-stimulating factor 1, OSTF1, FLJ20559, bA235O14.1. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | OSTF1 protein (1mg/ml) solution contains 20mM Tris-HCl buffer pH 8, 0.5mM DTT and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles. |
| Purity: | Greater than 95.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MSKPPPKPVK PGEGGQVKVF RALYTFEPRT PDELYFEEGD IIYITDMSDT NWWKGTSKGR TGLIPSNYVA EQAESIDNPL HEAAKRGNLS WLRECLDNRV GVNGLDKAGS TALYWACHGG HKDIVEMLFT QPNIELNQQN KLGDTALHAA AWKGYADIVQ LFLAKGARTD LRNIEKKLAF DMATNAACAS LLKKKQGTDA VRTLSNAEDY LDDEDSDLEH HHHHH |
OSTF1 is an intracellular protein produced by osteoclasts that induces bone resorption, via signaling cascade which results in the secretion of factors enhancing osteoclast formation and activity.
OSTF1 Human Recombinant produced in E.Coli is a monomeric, non-glycosylated, polypeptide chain containing 225 amino acids (1-217) and having a molecular mass of 25.1kDa. The OSTF1 is fused to an 8 amino acid His Tag at C-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | OSTF1: Induces bone resorption, acting probably through a signaling cascade which results in the secretion of factor(s) enhancing osteoclast formation and activity. |
| UniProt Protein Details: | Protein type:Adaptor/scaffold; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 9q21.13 Cellular Component: extracellular region; intracellular Molecular Function:protein binding Biological Process: neutrophil degranulation; ossification; signal transduction |
| NCBI Summary: | Osteoclast-stimulating factor-1 is an intracellular protein produced by osteoclasts that indirectly induces osteoclast formation and bone resorption (Reddy et al., 1998 [PubMed 10092216]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q92882 |
| NCBI GenInfo Identifier: | 108885279 |
| NCBI Gene ID: | 26578 |
| NCBI Accession: | Q92882.2 |
| UniProt Secondary Accession: | Q92882,Q5W126, Q96IJ4, |
| UniProt Related Accession: | Q92882 |
| Molecular Weight: | 24kDa |
| NCBI Full Name: | Osteoclast-stimulating factor 1 |
| NCBI Synonym Full Names: | osteoclast stimulating factor 1 |
| NCBI Official Symbol: | OSTF1�� |
| NCBI Official Synonym Symbols: | OSF; SH3P2; bA235O14.1�� |
| NCBI Protein Information: | osteoclast-stimulating factor 1 |
| UniProt Protein Name: | Osteoclast-stimulating factor 1 |
| Protein Family: | Osteoclast-stimulating factor |
| UniProt Gene Name: | OSTF1�� |
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