Cell Biology Recombinant Proteins
Human NCAM1 Recombinant Protein (RPES0202)
- SKU:
- RPES0202
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Cell Biology
Description
Human NCAM1 Recombinant Protein
Neural cell adhesion molecule 1 (NCAM-1) is a single-pass type I membrane protein, it belongs to a family of membrane-bound glycoproteins that are involved in Ca2+ independent cell matrix and homophilic or heterophilic cell-cell interactions. NCAM-1 is synthesized as a 761 aa preproprecursor that contains a 19 aa signal sequence, a 722 aa GPI-linked mature region, and a 20 aa C-terminal prosegment. The molecule contains five C-2 type Ig-like domains and two fibronectin type-III domains. NCAM-1 is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. Acting as a receptor for rabies virus, NCAM-1 in the adult brain shows a decline of sialylation relative to earlier developmental periods.
| Product Name: | Human NCAM1 Recombinant Protein (RPES0202) |
| Product Code: | RPES0202 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | CD56, NCAM-1, CD56 antigen, MSK39, N-CAM-1, NCAM-1, neural cell adhesion molecule 1, neural cell adhesion molecule, NCAM |
| Accession: | P13591-3 |
| Sequence: | Leu20-Pro603 |
| Fusion tag: | C-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Neural cell adhesion molecule 1 is produced by our Mammalian expression system and the target gene encoding Leu20-Pro603 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 65.5 kDa |
| AP Mol Mass: | 90-130 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM Tris, 150mM NaCl, pH8.0. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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