Human/Mouse CD11a Monoclonal Antibody [TS1/22.1.1.13](AGEL0233)

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SKU:
AGEL0233
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
TS1/22.1.1.13
Conjugation:
Unconjugated
Applications:
FC

Description

system_update_altDatasheet
Antibody Name:Human/Mouse CD11a Monoclonal Antibody
Antibody Code:AGEL0233
Size:100µg
Clone:TS1/22.1.1.13
Synonyms:Integrin alpha-L, Itgal, CD11 antigen-like family member A, LFA-1A, Lymphocyte antigen 15, Ly-15, CD11a
Host Species:Mouse
Species Reactivity:Human
Applications:FC
Concentration:1mg/mL
Isotype:IgG1
Conjugation:Unconjugated
Applications:FC
Recommended Dilution:Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10e6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage Buffer:PBS with 0.05% Proclin300
Storage:Keep as concentrated solution.Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Gene ID:368316408
Uniprot:P20701
Background:CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).
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