Human MGMT ELISA Kit

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SKU:
HUFI01727
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P16455
Sensitivity:
0.094ng/ml
Range:
0.156-10ng/ml
ELISA Type:
Sandwich
Synonyms:
MGMT, Methylated-DNA--protein-cysteine methyltransferase, 6-O-methylguanine-DNA methyltransferase, MGMT, O-6-methylguanine-DNA-alkyltransferase
Reactivity:
Human
Research Area:
Epigenetics and Nuclear Signaling

Description

Human MGMT ELISA

MGMT (O-6-Methylguanine-DNA Methyltransferase) is a Protein Coding gene. MGMT is a protein that repairs alkylated DNA bases, removing the alkyl group from the O-6 position of guanine. MGMT has been shown to interact with AAGAB, PIK3C2G and PIK3CG. Additionally, several transcript variants encoding different isoforms have been found for MGMT. The DNA Repair and Transcription pathways are linked to MGMT. The protein encoded by MGMT is a DNA glycosylase involved in the base excision repair (BER) pathway. Metastatic clear cell renal cell carcinoma is associated with MGMT.

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