Human MCSP / Melanoma Associated Chondroitin Sulfate Proteoglycan ELISA Kit

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SKU:
HUFI02620
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
Q6UVK1
Sensitivity:
0.094ng/ml
Range:
0.156-10ng/ml
ELISA Type:
Sandwich
Synonyms:
MCSP, AN2, CSPG4, HMW-MAA, MCSPG, MEL-CSPG, chondroitin sulfate proteoglycan 4, chondroitin sulfate proteoglycan 4, melanoma-associated, EC 3.6.3, HMW-MAA, MCSPChondroitin sulfate proteoglycan NG2, MCSPGMelanoma chondroitin sulfate proteoglycan, MEL-
Reactivity:
Human
Research Area:
Cardiovascular

Description

Human MCSP / Melanoma Associated Chondroitin Sulfate Proteoglycan ELISA

During early phases of melanoma cell spreading on endothelial basement membranes, a human MCSP (melanoma-associated chondroitin sulfate proteoglycan/CSPG4) is involved in maintaining cell-substratum interactions. CSPG4 is a membrane chondroitin sulfate proteoglycan that occurs in human malignant melanoma cells. Melanoma and acral lentiginous melanoma are two examples of CSPG4-related diseases. Chondroitin sulfate/dermatan sulfate metabolism and glycosaminoglycan metabolism are two CSPG4 pathways. Protein kinase binding and obsolete signal transducer activity are two GO annotations related to CSPG4.

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