Human MCPIP / Monocyte Chemoattractant Protein-induced Protein 1 ELISA Kit

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SKU:
HUFI02986
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
Q5D1E8
Sensitivity:
2.344pg/ml
Range:
3.906-250pg/ml
ELISA Type:
Sandwich
Synonyms:
Ribonuclease ZC3H12A, MCP-induced protein 1, Zinc finger CCCH domain-containing protein 12A, MCPIP1
Reactivity:
Human
Research Area:
Cardiovascular

Description

Human MCPIP / Monocyte Chemoattractant Protein-induced Protein 1 ELISA Kit

ZC3H12A is an MCP1-induced protein that acts as a transcriptional activator and causes cell death of cardiomyocytes, possibly via induction of genes associated with apoptosis. ZC3H12A has endonuclease activity and is involved in reorganization of chromatin and transcriptional regulation through deamination and subsequent targeted DNA methylation. ZC3H12A has a central role in cellular metabolism and energy production, especially under acute metabolic stress conditions such as ischemia. Diseases linked to ZC3H12A include cardiomyopathy and cancer.

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