Human LIN-28A / lin-28 homolog A ELISA Kit

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SKU:
HUFI01499
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
Q9H9Z2
Sensitivity:
0.094ng/ml
Range:
0.156-10ng/ml
ELISA Type:
Sandwich
Synonyms:
LIN28A, LIN-28A, CSDD1, LIN28, Tex17, ZCCHC1, CSDD1lin-28A, LIN-28, lin-28 homolog A, LIN28RNA-binding protein LIN-28, ZCCHC1protein lin-28 homolog A, Zinc finger CCHC domain-containing protein 1, zinc finger, CCHC domain containing 1
Reactivity:
Human
Research Area:
Epigenetics and Nuclear Signaling

Description

Human LIN-28A / lin-28 homolog A ELISA Kit

LIN-28A / lin-28 homolog A encodes an RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. LIN-28A / lin-28 homolog A functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. LIN-28A / lin-28 homolog A prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of LIN-28A / lin-28 homolog A is associated with embryonal tumor and atypical teratoid rhabdoid tumor.

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