Metabolism Recombinant Proteins

Human LDLR Recombinant Protein (RPES3717)

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SKU:
RPES3717
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Metabolism

Description

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Human LDLR Recombinant Protein

The low density lipoprotein receptor (LDLR) gene family is made up of cell surface receptors that are involved in ligand-mediated endocytosis. The low-density lipoprotein (LDL) is tightly bound to the cell membrane and incorporated into the cell, where it is broken down and cholesterol is released for HMG CoA reductase repression, the rate-limiting step in cholesterol synthesis. Familial hypercholesterolemia is an autosomal dominant illness caused by defects in the LDLR gene. Hypercholesterolemia is an example of an comdition linked to LDLR. Lipid homeostasis and folate metabolism are related pathways of LDLR. Human LDLR Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.

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