Signal Transduction Recombinant Proteins
Human Kallikrein 4/KLK4 Recombinant Protein (RPES2848)
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- SKU:
- RPES2848
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Signal Transduction
Description
system_update_altDatasheet
Human Kallikrein 4/KLK4 Recombinant Protein
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many Kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen members of the Kallikrein subfamily located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.
| Product Name: | Human Kallikrein 4/KLK4 Recombinant Protein (RPES2848) |
| Product Code: | RPES2848 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | Kallikrein-4, Enamel Matrix Serine Proteinase 1, Kallikrein-Like Protein 1, KLK-L1, Prostase, Serine Protease 17, KLK4, EMSP1, PRSS17, PSTS,AI2A1,ARM1,EMSP,kallikrein,KLK-L1 |
| Accession: | Q9Y5K2 |
| Sequence: | Ser27-Ser254 |
| Fusion tag: | C-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Kallikrein 4 is produced by our Mammalian expression system and the target gene encoding Ser27-Ser254 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 25.4 kDa |
| AP Mol Mass: | 30 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 20mM TrisHCl, 150mM NaCl, pH 8.0. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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