Human Kallikrein 2/KLK2 Recombinant Protein (RPES2827)

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SKU:
RPES2827
Product Type:
Recombinant Protein
Species:
Human

Description

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Human Kallikrein 2/KLK2 Recombinant Protein

Kallikrein-2 (KLK2) is a secreted serine protease that belongs to the peptidase S1 family of Kallikrein subfamily. KLK2 contains 1 peptidase S1 domain. It is highly expressed in the human prostate gland. KLK2 can cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin, but Preferential cleavages of Arg-|-Xaa bonds in small molecule substrates. It also highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met-|-Xaa or Leu-|-Xaa. KLK2 is inhibited by serpins such as protein C inhibitor, antichymotrypsin, and plasminogen. KLK2 is considered to be a biomarker for prostate cancer.

Product Name:Human Kallikrein 2/KLK2 Recombinant Protein (RPES2827)
Product Code:RPES2827
Size:10µg
Species:Human
Expressed Host:Human Cells
Synonyms:Kallikrein-2, Glandular Kallikrein-1, hGK-1, Tissue Kallikrein-2, KLK2
Accession:P20151
Sequence:Pro19-Pro261
Fusion tag:C-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Kallikrein 2 is produced by our Mammalian expression system and the target gene encoding Pro19-Pro261 is expressed with a 6His tag at the C-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:27.9 kDa
AP Mol Mass:31 kDa
Formulation:Supplied as a 0.2 µm filtered solution of 20mM Citrate, 150mM NaCl, pH 3.5.
Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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