Human Interleukin7D/IL7D Recombinant Protein (RPES1671)

Human Interleukin7D/IL7D Recombinant Protein

The Interleukin-17 family of proteins, which include six members (IL-17, IL-17A through IL-17F), are secreted proteins that have a conserved cysteine knot fold near the C-terminus but significant sequence divergence at the N-terminus. IL-17A and IL-17F proteins are proinflammatory cytokines that induce local cytokine production and are involved in the regulation of immunological processes. Among IL-17 family members, IL-17D is most closely related to IL-17B, sharing 27% aa sequence homology. IL-17D is highly expressed in skeletal muscle, heart, fat tissue, lungs, pancreas, and nervous system. IL-17D, like several other IL-17 family members, affects immune responses indirectly by increasing the production of myeloid growth factors and chemokines such as IL-6, IL-8, and GM-CSF. IL-17D has also been shown to suppress the proliferation of myeloid progenitors in colony formation assays. Human Interleukin7D/IL7D Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.