Human INPP5D / SHIP1  ELISA Kit

(No reviews yet) Write a Review
SKU:
HUFI02057
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
Q92835
Sensitivity:
46.875pg/ml
Range:
78.125-5000pg/ml
ELISA Type:
Sandwich
Synonyms:
INPP5D, MGC104855, MGC142140, MGC142142, SHIP, SHIP1, SIP-145, hp51CN, p150Ship, hp51CN, Inositol polyphosphate-5-phosphatase of 145 kDa, SIP-145, SH2 domain-containing inositol-5'-phosphatase 1, SH2 domain-containing inositol phosphatase 1, SHIP-1,
Reactivity:
Human
Research Area:
Cell Death

Description

Human INPP5D / SHIP1  ELISA

INPP5D / SHIP1 encodes a protein with an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of INPP5D / SHIP1 is restricted to hematopoietic cells and is partly localized to the nucleus, where INPP5D / SHIP1 may be involved in nuclear inositol phosphate signaling processes. INPP5D / SHIP1 functions as a negative regulator of myeloid cell proliferation and survival. Mutations in INPP5D / SHIP1 have been associated with Crohn's Disease and Lymphoproliferative Syndrome.

View AllClose

0 Reviews

View AllClose