Human IMPA2/IMPase 2 Recombinant Protein (RPES1504)
- SKU:
- RPES1504
- Product Type:
- Recombinant Protein
- Species:
- Human
Description
Human IMPA2/IMPase 2 Recombinant Protein
Inositol monophosphatase 2, also known as Inositol-1(or 4)-monophosphatase 2, Myo-inositol monophosphatase A2 and IMPA2, is an enzyme which belongs to the inositol monophosphatase family. IMPA2 catalyzes the dephosphoylration of inositol monophosphate with cofactor Magnesium and Inhibited by high Li+ and restricted Mg2+ concentrations. IMPA2 plays an important role in phosphatidylinositol signaling. IMPA2 can use the myo-inositol monophosphates, scylloinositol 1,4-diphosphate, glucose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. IMPA2 is a pharmacological target for lithium Li(+) action in brain, it is considered to have a role in schizophrenia and bipolar disorder.
| Product Name: | Human IMPA2/IMPase 2 Recombinant Protein (RPES1504) |
| Product Code: | RPES1504 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | Inositol Monophosphatase 2, IMP 2, IMPase 2, Inositol-1(or 4)-Monophosphatase 2, Myo-Inositol Monophosphatase A2, IMPA2, IMP.18P |
| Accession: | O14732 |
| Sequence: | Met 1-Lys288 |
| Fusion tag: | N-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Inositol Monophosphatase 2 is produced by our E.coli expression system and the target gene encoding Met1-Lys288 is expressed with a 6His tag at the N-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 33.5 kDa |
| AP Mol Mass: | 30 kDa |
| Formulation: | Supplied as a 0.2 µm filtered solution of 20mM Tris, 2mM DTT, pH 8.0. |
| Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C. |
| Stability and Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
Related Products
Human IMPA2 Recombinant Protein (RPPB1849)
Enzymes Recombinant Proteins
Human BMP 2 Protein Recombinant Protein (RPPB0092)
Cytokines Recombinant Proteins
Human MMP-2 Recombinant Protein (RPES4601)
Human IRF 2 Recombinant Protein (RPPB0412)
Cytokines Recombinant Proteins
