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Description
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Human ILRL2 Recombinant Protein
Interleukin-1 receptor-like 2 is a protein that in humans is encoded by the IL1RL2 gene; belongs to the interleukin-1 receptor family.IL1RL2 is the receptor for interleukin-36 (IL36A; IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B; MAPK and other pathways.
| Product Name: | Human ILRL2 Recombinant Protein (RPES1057) |
| Product Code: | RPES1057 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | Interleukin-1 receptor-like 2,IL1RL2,IL-36 receptor,IL-36R,IL-1Rrp2,IL1R-rp2, |
| Accession: | Q9HB29 |
| Sequence: | Asp20-Tyr337 |
| Fusion tag: | C-Fc |
| Activity: | Immobilized Human IL-36RA(Cat: PKSH033614) at 0.5µg/ml(100 ?l/well) can bind Human IL-1RL2-Fc. The ED50 of Human IL-1RL2-Fc is 22.47 ug/ml . |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Interleukin-1 receptor-like 2 is produced by our Mammalian expression system and the target gene encoding Asp20-Tyr337 is expressed with a Fc tag at the C-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 63.1 kDa |
| AP Mol Mass: | 80-110 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of PBS; pH7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Additional Information
Product Type: |
Recombinant Protein |
Species: |
Human |
Research Area: |
Immunology |