Interleukin-1 receptor-like 2 is a protein that in humans is encoded by the IL1RL2 gene; belongs to the interleukin-1 receptor family.IL1RL2 is the receptor for interleukin-36 (IL36A; IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B; MAPK and other pathways.
Immobilized Human IL-36RA(Cat: PKSH033614) at 0.5µg/ml(100 ?l/well) can bind Human IL-1RL2-Fc. The ED50 of Human IL-1RL2-Fc is 22.47 ug/ml .
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Interleukin-1 receptor-like 2 is produced by our Mammalian expression system and the target gene encoding Asp20-Tyr337 is expressed with a Fc tag at the C-terminus.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
63.1 kDa
AP Mol Mass:
80-110 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of PBS; pH7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
