Human IL18RAP/IL1R7 Recombinant Protein (RPES1133)

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SKU:
RPES1133
Product Type:
Recombinant Protein
Species:
Human

Description

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Human IL18RAP/IL1R7 Recombinant Protein

IL-18RAP is a single-pass type I membrane protein and contains two Ig-like C2-type domains and one TIR domain, IL18RAP can be induced by IFN-alpha and IL12 in nature killer cells and T-cells. The coexpression of IL18R1 and IL18RAP is required for the activation of NF-kappa B and JNK in response to IL-18.Defects in IL18RAP are associated with Coeliac disease.

Product Name:Human IL18RAP/IL1R7 Recombinant Protein (RPES1133)
Product Code:RPES1133
Size:10µg
Species:Human
Expressed Host:Human Cells
Synonyms:ACPL,CD218b,CDw218b,IL-18R-beta,IL-18RAcP,IL-18Rbeta,IL-1R-7,IL-1R7,IL-1RAcPL,IL18RB
Accession:O95256
Sequence:Phe20-Arg356
Fusion tag:C-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Interleukin-18 receptor accessory protein is produced by our Mammalian expression system and the target gene encoding Phe20-Arg356 is expressed with a 6His tag at the C-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:39.4 kDa
AP Mol Mass:56 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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