Metabolism Recombinant Proteins

Human IDH1 Recombinant Protein (R132H, C-8His) (RPES2708)

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SKU:
RPES2708
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Metabolism

Description

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Human IDH1 Recombinant Protein (R132H, C-8His)

Isovalerate dehydrogenase [NADP] Cytoplasmic (IDH1) is part of the isocitrate and isopropylmalate dehydrogenases family. The protein IDH1 is a dimer that binds one magnesium or manganese ion per subunit. Metaphyseal chondromatosis with aciduria is observed in patients who have a mutation of IDH1. Glioma occurs as a result of mutations of IDH1. The enzyme IDH is involved in the regeneration of NADPH for intracellular reductions, such as conversion of 2; 4-dienoyl-CoAs to 3-enoyl-CoAs; and peroxisomal reactions that consume 2-oxoglutarate, such as alpha-hydroxylation of phytanic. Human IDH1 Recombinant Protein (R132H, C-8His) is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.

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