Human HSD11B1 ELISA Kit

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SKU:
HUFI01853
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P28845
Sensitivity:
0.094ng/ml
Range:
0.156-10ng/ml
ELISA Type:
Sandwich
Synonyms:
HSD11B1, 11-beta-hydroxysteroid dehydrogenase 1, 11-DH, 11-beta-HSD1, HSD11, 11-beta-HSD1, HDL, HSD11B, HSD11L, 11-DH
Reactivity:
Human
Research Area:
Metabolism

Description

Human HSD11B1 ELISA Kit

The protein encoded by HSD11B1 is a member of the aldo-keto reductase superfamily. This protein catalyzes the conversion of progesterone to 11-deoxycorticosterone, and thereby participates in the regulation of mineralocorticoid levels. Mutations in HSD11B1 have been associated with familial glucocorticoid deficiency type 2, a disorder characterized by abnormalities in cortisol production and resistance to mineralocorticoids. Alternatively spliced transcript variants encoding different isoforms have been found for HSD11B1.

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