Human HLA-DR Monoclonal Antibody [L243](AGEL0413)

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SKU:
AGEL0413
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2a
Clone:
L243
Conjugation:
Unconjugated
Applications:
FC
Applications:
WB
Applications:
IHC
Applications:
IP

Description

system_update_altDatasheet
Antibody Name:Human HLA-DR Monoclonal Antibody
Antibody Code:AGEL0413
Size:100µg
Clone:L243
Synonyms:HLA class II histocompatibility antigen DR alpha/ DRB1-15 beta chain, MHC class II antigen DRA, HLA-DRA1/DRB1, DRA/DRB1
Host Species:Mouse
Species Reactivity:Human
Applications:FC, WB, IHC, IP
Concentration:1mg/mL
Isotype:IgG2a
Conjugation:Unconjugated
Applications:FC, WB, IHC, IP
Recommended Dilution:Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10e6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage Buffer:PBS with 0.05% Proclin300
Storage:Keep as concentrated solution.Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Gene ID:31223123
Uniprot:P01903
Background:The LN3 monoclonal antibody reacts with the HLA-DR antigen, a member of MHC class II molecules. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kD α (heavy) chain and a 27 kD β (light) chain. It is expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells
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