Human GPER / G-protein coupled estrogen receptor 1 ELISA Kit

(No reviews yet) Write a Review
SKU:
HUFI01093
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
Q99527
Sensitivity:
0.188ng/ml
Range:
0.313-20ng/ml
ELISA Type:
Sandwich
Synonyms:
GPER, CEPR, CMKRL2, DRY12, FEG-1, GPCR-BR, GPR30, LERGU2, LERGU, LyGPR, FEG-1mER, G-protein coupled receptor 30, Chemoattractant receptor-like 2, chemokine receptor-like 2, constitutively expressed peptide-like receptor, IL8-related receptor DRY12, F
Reactivity:
Human
Research Area:
Cell Death

Description

Human GPER / G-protein coupled estrogen receptor 1 ELISA Kit

GPER is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that is found in the endoplasmic reticulum. GPER binds oestrogen and activates a number of downstream signalling pathways, including adenylate cyclase stimulation and an increase in cyclic AMP levels, as well as intracellular calcium mobilisation and phosphatidylinositol 3,4,5-triphosphate synthesis in the nucleus. As a result, GPER is involved in the rapid nongenomic signalling events that occur after oestrogen stimulation of cells and tissues. GPER has been linked to bone and nervous system development, metabolism, cognition, male fertility, and uterine function, among other biological processes. Estrogen-Receptor Negative Breast Cancer and Teeth Hard Tissue Disease are two diseases linked to GPER1.

View AllClose

0 Reviews

View AllClose