Cell Death Recombinant Proteins

Human GAPDH Recombinant Protein (RPES2182)

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SKU:
RPES2182
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Cell Death

Description

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Human GAPDH Recombinant Protein

Glyceraldehyde 3-phosphate dehydrogenase (GAPDH or G3PDH) is an enzyme of about 37kDa that is consisdered as a cellular enzyme involved in glycolysis. It catelyzes the sixth step of glycolysis. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a pleiotropic enzyme that is overexpressed in apoptosis and in several human chronic pathologies. Its role as a mediator for cell death has also been highlighted. A recent report suggests that GAPDH may be genetically associated with late-onset of Alzheimer's disease. Besides, deprenyl, which has originally been used as a monoamine oxidase inhibitor for Parkinson's disease, binds to GAPDH and displays neuroprotective actions.

Product Name:Human GAPDH Recombinant Protein (RPES2182)
Product Code:RPES2182
Size:50µg
Species:Human
Expressed Host:E.coli
Synonyms:G3PD,GAPD,HEL-S-162eP
Accession:P04406
Sequence:Met 1-Glu 335
Fusion tag:N-His
Endotoxin:Please contact us for more information.
Protein Construction:A DNA sequence encoding the human GAPDH (P04406) (Met 1-Glu 335) was expressed, with a polyhistidine tag at the N-terminus.
Purity:> 93 % as determined by reducing SDS-PAGE.
Mol Mass:38 kDa
AP Mol Mass:38 kDa
Formulation:Lyophilized from sterile 50mM Tris, 30% glycerol, pH 7.5
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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