Epigenetics & Nuclear Signaling Recombinant Proteins
Human Fumarase/FH Recombinant Protein (RPES4400)
- SKU:
- RPES4400
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Epigenetics & Nuclear Signaling
Description
Human Fumarase/FH Recombinant Protein
Fumaratase catalyses the reversible hydration/dehydration of fumarate to S-malate and is involved in the tricarboxylic acid or Krebs cycle. Fumarate exists in two forms: a cytosolic form and an N-terminal extension of the mitochondrial form. The N-terminal extended form of the protein is intended for the mitochondrion, where the same process as in the cytoplasm takes place. Fumarate is considered a tumor suppressor, and its deficiency may lead to progressive encephalopathy, cerebral atrophy, and developmental delay. Human Fumarase/FH Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
| Product Name: | Human Fumarase/FH Recombinant Protein (RPES4400) |
| Product Code: | RPES4400 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | Fumarate Hydratase Mitochondrial, Fumarase, FH,FMRD,HLRCC,LRCC,MCL,MCUL1 |
| Accession: | P07954 |
| Sequence: | Ala45-Lys510 |
| Fusion tag: | |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Fumarase is produced by our E.coli expression system and the target gene encoding Ala45-Lys510 is expressed. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 50.2 kDa |
| AP Mol Mass: | 45 kDa |
| Formulation: | Supplied as a 0.2 µm filtered solution of 20mM Tris, pH 8.0. |
| Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C. |
| Stability and Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
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