Immunology Recombinant Proteins
Human Fibronectin/FN Recombinant Protein (RPES2695)
- SKU:
- RPES2695
Description
Human Fibronectin/FN Recombinant Protein
Fibronectin is a high-molecular weight glycoprotein of the extracellular matrix that binds to membrane-spanning receptor proteins called integrins. Similar to integrins; fibronectin binds extracellular matrix components such as collagen; fibrin; and heparan sulfate proteoglycans. Fibronectin plays a major role in cell adhesion; growth; migration; and differentiation; and it is important for processes such as wound healing and embryonic development. Altered fibronectin expression; degradation; and organization has been associated with a number of pathologies; including cancer and fibrosis. Anastellin binds fibronectin and induces fibril formation. This fibronectin polymer; named superfibronectin; exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth; angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling.
| Product Name: | Human Fibronectin/FN Recombinant Protein (RPES2695) |
| Product Code: | RPES2695 |
| Size: | 20µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | Fibronectin, FN1, CIG, ED-B, FINC, FN, FNZ, GFND, GFND2, LETS, MSF |
| Accession: | P02751 |
| Sequence: | Glu5-Thr95 |
| Fusion tag: | N-His-Avi |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Fibronectin is produced by our E.coli expression system and the target gene encoding Glu5-Thr95 is expressed with a 6His; Avi tag at the N-terminus. |
| Purity: | > 95% as determined by reducing SDS-PAGE. |
| Mol Mass: | 13.4 kDa |
| AP Mol Mass: | 13 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of PBS; pH7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Additional Information
Product Type: |
Recombinant Protein |
Species: |
Human |
Research Area: |
Immunology |
Related Products
Human Fibronectin/FN Recombinant Protein (RPES2409)
Human Fibronectin/FN Recombinant Protein (His tag)
Human Fibronectin Recombinant Protein (RPPB3702)
Natural Proteins Recombinant Proteins
