Human F2RL1 Full-Length Bioactive Membrane Protein (HDFP018)

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SKU:
HDFP018

Description

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Product nameHuman F2RL1 full length protein-synthetic nanodisc
Size:10ug
Product SKU:HDFP018
Product CategoryFull Length Transmembrane Proteins
Target:F2RL1
Uniprot:P55085
Description:Human F2RL1 full length protein-synthetic nanodisc
Molecular Weight:The human full length F2RL1 protein has a MW of 44.1 kDa
Protein Family:Druggable Genome, GPCR, Transmembrane
Protein Pathways:Neuroactive ligand-receptor interaction
Storage & Shipping:Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Synonyms:GPR11; PAR2
Expression System:HEK293
Formulation:Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
Background:A member of the G-protein coupled receptor 1 family of proteins. The encoded cell surface receptor is activated through proteolytic cleavage of its extracellular amino terminus, resulting in a new amino terminus that acts as a tethered ligand that binds to an extracellular loop domain. Activation of the receptor has been shown to stimulate vascular smooth muscle relaxation, dilate blood vessels, increase blood flow, and lower blood pressure. This protein is also important in the inflammatory response, as well as innate and adaptive immunity.
Delivery:In Stock
UsageResearch use only
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Additional Information

Product Type:
Recombinant Protein
Protein Type:
Full-Length Bioactive Membrane Protein
Species:
Human
Uniprot:
P55085
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