Neuroscience Recombinant Proteins
Human EphB2 Recombinant Protein (RPES1483)
- SKU:
- RPES1483
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Neuroscience
Description
Human EphB2 Recombinant Protein
Ephrin type-B receptor 2(EPHB2) belongs to the protein kinase superfamily and Ephrin receptor subfamily. EPHB2 contains 1 Eph LBD domain; 2 fibronectin type-III domains; 1 protein kinase domain and 1 SAM domain. Ephrin receptors and their ligands; the ephrins; mediate numerous developmental processes; particularly in the nervous system. Based on their structures and sequence relationships; ephrins are divided into the ephrin-A (EFNA) class; which are anchored to the membrane by a glycosylphosphatidylinositol linkage; and the ephrin-B (EFNB) class; which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family.
| Product Name: | Human EphB2 Recombinant Protein (RPES1483) |
| Product Code: | RPES1483 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | CAPB,DRT,EK5,EPHT3,ERK,Hek5,PCBC,Tyro5,EPHB2,Ephrin type-B receptor 2 |
| Accession: | P29323-3 |
| Sequence: | Val19-Ser482 |
| Fusion tag: | C-Fc |
| Activity: | Immobilized Human EphB2-Fc at 2µg/ml(100 ?l/well) can bind Human EFNB2-His(Cat: PKSH032395). |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Ephrin type-B receptor 2 is produced by our Mammalian expression system and the target gene encoding Val19-Ser482 is expressed with a Fc tag at the C-terminus. |
| Purity: | > 90 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 78.5 kDa |
| AP Mol Mass: | 120 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of PBS; pH7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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