Human ELN / Elastin ELISA Kit

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SKU:
HUFI01225
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P15502
Sensitivity:
0.281ng/ml
Range:
0.469-30ng/ml
ELISA Type:
Sandwich
Synonyms:
ELN, Elastin
Reactivity:
Human
Research Area:
Cell Biology

Description

Human ELN / Elastin ELISA Kit

ELN/Elastin is one of the two components of elastic fibers. Elastic fibers make up part of the extracellular matrix and provide suppleness to organs and tissues such as the heart, skin, lungs, ligaments, and blood vessels. ELN/Elastin has numerous hydrophobic amino acids such as glycine and proline, which create mobile hydrophobic areas bounded by crosslinks between lysine residues. Protein degradation products, known as elastin-derived peptides or elastokines, bind the elastin receptor complex and other receptors to stimulate monocyte migration and proliferation. Elastokines can aid in the growth of cancer. Supravalvular aortic stenosis (SVAS) and autosomal dominant cutis laxa are linked to deletions and mutations in the ELN/Elastin gene.

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