Human DVL1 / Segment polarity dishevelled homolog DVL-1 ELISA Kit

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SKU:
HUFI01470
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
O14640
Sensitivity:
0.094ng/ml
Range:
0.156-10ng/ml
ELISA Type:
Sandwich
Synonyms:
DVL1, Segment polarity protein dishevelled homolog DVL-1, Dishevelled-1, DSH homolog 1, DVL, dishevelled, dsh homolog 1, Drosophila, dishevelled 1, homologous to Drosophila dsh,
Reactivity:
Human
Research Area:
Metabolism

Description

Human DVL1 / Segment polarity dishevelled homolog DVL-1 ELISA

DVL1 (Dishevelled Segment Polarity Protein 1) is found in the nuclei of developing cells, and presumed to have a role in transcriptional regulation. DVL1 mutations are associated with various disorders including tooth agenesis (Dentinogenesis Imperfecta Type II), limb malformations (Micromelic Syndrome Type 1) and cancer (WNT4-associated colorectal carcinoma). The human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation and serves as a transducer molecule for developmental processes, including segmentation and neuroblast specification.

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