Human DIO2 / Type II iodothyronine deiodinase ELISA Kit

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SKU:
HUFI00730
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
Q92813
Sensitivity:
0.094ng/ml
Range:
0.156-10ng/ml
ELISA Type:
Competitive
Synonyms:
DIO2, Type-II 5'-deiodinase, Type 2 DI, 5DII, DIOII, ITDI2, TXDI2
Reactivity:
Human
Research Area:
Metabolism

Description

Human DIO2 / Type II iodothyronine deiodinase ELISA Kit

DIO2 / Type II iodothyronine deiodinase catalyzes the conversion of prohormone thyroxine to the bioactive thyroid hormone by outer ring 5'-deiodination. DIO2 / Type II iodothyronine deiodinase is thought to be responsible for the 'local' production of T3, and thus important in influencing thyroid hormone action in the brain and thyroid gland. DIO2 / Type II iodothyronine deiodinase has also been reported to be highly expressed in thyroid glands of patients with follicular adenomas and graves disease.

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