Human Diamine Oxidase/AOC1 Recombinant Protein (RPES2288)
(No reviews yet)
Write a Review
- SKU:
- RPES2288
- Product Type:
- Recombinant Protein
- Species:
- Human
Description
system_update_altDatasheet
Human Diamine Oxidase/AOC1 Recombinant Protein
Amiloride-sensitive amine oxidase (AOC1) belongs to the copper/topaquinone oxidase family. The protein exists as homodimer by disulfide and mainly located in placenta and kidney. AOC1 catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. Placental DAO is thought to play a role in the regulation of the female reproductive function. The activity of this protein can be inhibited by amiloride in a competitive manner. It is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels.
| Product Name: | Human Diamine Oxidase/AOC1 Recombinant Protein (RPES2288) |
| Product Code: | RPES2288 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | Amiloride-sensitive amine oxidase [copper-containing],DAO,Diamine oxidase,Amiloride-binding protein 1,Amine oxidase copper domain-containing protein 1,Histaminase,Kidney amine oxidase,KAO,AOC1,ABP1, DAO1 |
| Accession: | P19801 |
| Sequence: | Glu20-Val751 |
| Fusion tag: | C-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Amiloride-binding protein 1 is produced by our Mammalian expression system and the target gene encoding Glu20-Val751 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 84.4 kDa |
| AP Mol Mass: | 90 kDa |
| Formulation: | Supplied as a 0.2 µm filtered solution of 20mM TrisHCl, 150mM NaCl,10% Glycerol,pH7.5. |
| Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C. |
| Stability and Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
Related Products
