Human Cytokeratin ELISA Kit

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SKU:
HUFI01869
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P08779
Sensitivity:
0.094ng/ml
Range:
0.156-10ng/ml
ELISA Type:
Sandwich
Synonyms:
KRT16, CytokeRatin-16, CK-16, KeRatin-16, CK16, K1CP, NEPPK, FNEPPK, KRT16A
Reactivity:
Human
Research Area:
Cell Biology

Description

Human Cytokeratin ELISA Kit

KRT16 has been linked to cancer, specifically bladder cancer which makes it an important marker for cancer research. KRT16 has been shown to interact with BCAR1 and UBR5. An important paralog of KRT16 is DENND2C. Mutations in KRT16 have been found as a cause of scalded skin syndrome, also known as Lyell Syndrome. The mutations lead to a complete absence of Keratin 16 from the cell membranes in affected areas, which reveals the underlying tissue. These mutations are caused by cytosine-to-thymine point mutation, which occur at position 1825 of the KRT16 gene.

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