Human Cystatin C/CST3 Recombinant Protein (RPES1701)
- SKU:
- RPES1701
- Product Type:
- Recombinant Protein
- Species:
- Human
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Description
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Human Cystatin C/CST3 Recombinant Protein
Cystatin C is a member of family 2 of the cystatin superfamily. It is ubiquitous in human tissues and body fluids and mainly used as a biomarker of kidney function. Cystatin C inhibits many cysteine proteases such as papain and Cathepsins B; H; K; L and S. As an inhibitor of cysteine proteinases; Cystatin C is thought to serve an important physiological role as a local regulator of this enzyme activity. Recently; it has been studied for its role in predicting new-onset or deteriorating cardiovascular disease. It also seems to play a role in brain disorders involving amyloid (a specific type of protein deposition); such as Alzheimer's disease.
| Product Name: | Human Cystatin C/CST3 Recombinant Protein (RPES1701) |
| Product Code: | RPES1701 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | Cystatin-C,Cystatin-3,Gamma-trace,Neuroendocrine basic polypeptide,Post-gamma-globulin,CST3 |
| Accession: | P01034 |
| Sequence: | Ser27-Ala146 |
| Fusion tag: | C-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Cystatin C is produced by our Mammalian expression system and the target gene encoding Ser27-Ala146 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 90 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 14.4 kDa |
| AP Mol Mass: | 15-18 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of 10mM PB; 200mM Nacl; pH6.5. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |