Human CYP7A1 / Cholesterol 7-alpha-monooxygenase ELISA Kit

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SKU:
HUFI00931
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P22680
Sensitivity:
0.188ng/ml
Range:
0.313-20ng/ml
ELISA Type:
Sandwich
Synonyms:
CYP7A1, Cytochrome P450 7A1, Cholesterol 7-alpha-monooxygenase, CYPVII, Cholesterol 7-alpha-hydroxylase
Reactivity:
Human
Research Area:
Metabolism

Description

Human CYP7A1 / Cholesterol 7-alpha-monooxygenase ELISA Kit

CYP7A1 belongs to the cytochrome P450 superfamily of proteins. Monooxygenases in the cytochrome P450 family monooxygenate a variety of chemicals and reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids. CYP7A1 is an endoplasmic reticulum membrane protein and is the first component in the cholesterol catabolic pathway in the liver, which transforms cholesterol to bile acids. Defects in bile acid synthesis are associated with polymorphisms within the promoter of the CYP7A1 gene. Hypercholesterolemia due to CYP7A1 deficiency and Sitosterolemia are two examples of diseases linked to CYP7A1.

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