Immunology Recombinant Proteins

Human Cyclophilin A Recombinant Protein (RPES3919)

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SKU:
RPES3919
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Immunology

Description

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Human Cyclophilin A Recombinant Protein

Peptidyl-prolyl cis-trans isomerase A is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family; which catalyzes the cis-trans isomerization of proline imidic peptide bonds. Cyclophilin A has been shown to regulate numerous biological processes, including intracellular signaling, transcription, inflammation, and apoptosis. Cyclophilin is also present in a variety of viruses, including HIV-1; and it has been suggested to be involved in functions such as viral assembly and infection. The immunosuppressive activity of cyclosporins has been correlated with their ability to form complexes with cyclophilins that inhibit calcineurin phosphatase activity and prevent incorporation of cyclophilin into viral particles. The cyclosporin/cyclophilin complex binds and inactivates calcineurin, making it an advantageous inhibitor for studying calcineurin activity. Human Cyclophilin A Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.

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