Human Complement factor I / CFI ELISA Kit

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SKU:
HUFI00848
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
P05156
Sensitivity:
56.25ng/ml
Range:
93.75-6000ng/ml
ELISA Type:
Sandwich
Synonyms:
CFI, C3b Inactivator, C3BINA, IF, KAF, AHUS3, FIC3b-INA, C3B, C4B inactivator, C3b-inactivator, complement component I, complement control protein factor I, complement factor I heavy chain, I factor, complement,, Konglutinogen-activating factor, ligh
Reactivity:
Human
Research Area:
Immunology

Description

Human Complement factor I / CFI ELISA Kit

Complement factor I/CFI is a serine proteinase that is essential for controlling the complement cascade. Complement factor I insufficiency is an autosomal recessive disorder caused by a lack of the CFI gene. A variant in the TFR1 gene (also known as CD79A) has been linked to a propensity for atypical hemolytic uremic syndrome, which is a condition involving acute renal failure, microangiopathic hemolytic anemia and thrombocytopenia. The Immune System and Lectin Pathway are among CFI related pathways.

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