Signal Transduction Recombinant Proteins
Human CLIC4 Recombinant Protein (RPES2154)
- SKU:
- RPES2154
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Signal Transduction
Description
Human CLIC4 Recombinant Protein
Chloride Intracellular Channel Protein 4 (CLIC4) is a 253 amino acid single-pass membrane protein that localizes to both the nucleus and the cytoplasm and contains one GST C-terminal domain. CLIC4 is expressed in various tissues and exhibits an intracellular vesicular pattern in Panc-1 cells (pancreatic cancer cells). CLIC4 acts as a monomer which is able to form selective ion channels in target proteins; thus facilitating the transport of chloride and other ions. CLIC4 is believed to have a role in apoptosis and is able to translocate to the nucleus under stress conditions. CLIC4 has alternate cellular functions like a potential role in angiogenesis or in maintaining apical-basolateral membrane polarity during mitosis and cytokinesis.
| Product Name: | Human CLIC4 Recombinant Protein (RPES2154) |
| Product Code: | RPES2154 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | E.coli |
| Synonyms: | CLIC4L,H1,huH1,MTCLIC,p64H1 |
| Accession: | Q9Y696-1 |
| Sequence: | Met 1-Lys253 |
| Fusion tag: | N-6His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human Chloride Intracellular Channel Protein 4 is produced by our E.coli expression system and the target gene encoding Met1-Lys253 is expressed with a 6His tag at the N-terminus. |
| Purity: | > 95 % as determined by reducing SDS-PAGE. |
| Mol Mass: | 30.9 kDa |
| AP Mol Mass: | 32 kDa |
| Formulation: | Supplied as a 0.2 µm filtered solution of 20mM TrisHCl; 100mM NaCl; 1mM DTT; pH 8.0. |
| Shipping: | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt; store it immediately at<-20°C. |
| Stability and Storage: | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
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