Human CKLFSF6 / Chemokine Like Factor Superfamily 6 ELISA Kit

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SKU:
HUFI02324
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
Q9NX76
Sensitivity:
0.094ng/ml
Range:
0.156-10ng/ml
ELISA Type:
Sandwich
Synonyms:
CKLFSF6, CKLF-like MARVEL transmembrane domain-containing protein 6, CMTM6
Reactivity:
Human
Research Area:
Signal Transduction

Description

Human CKLFSF6 / Chemokine Like Factor Superfamily 6 ELISA Kit

CKLFSF6 / Chemokine Like Factor Superfamily 6 is located in a cluster on chromosome 3 and widely expressed in many tissues. CKLFSF6 / Chemokine Like Factor Superfamily 6 regulates recycling and plasma membrane expression of PD-L1/CD274, which is critical for immune tolerance and antitumor immunity. CKLFSF6 / Chemokine Like Factor Superfamily 6 protects PD-L1/CD274 from being targeted for lysosomal degradation, likely by preventing its STUB1-mediated ubiquitination.

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