Human CDO/CDON Recombinant Protein (RPES3555)
- SKU:
- RPES3555
- Product Type:
- Recombinant Protein
- Species:
- Human
Description
system_update_altDatasheet
Human CDO/CDON Recombinant Protein
CDO (CAMrelated/down-regulatedby oncogenes) is a member of the Immunoglubulin (Ig) superfamily, Ig/Fibronectin (FN)type III repeat family of cell surface proteins. Human CDO is a type I transmembrane (TM) glycoprotein. It is synthesized as a 1287 amino acid (aa) precursorthat contains a 25 aa signal sequence, a 938 aa extracellular domain (ECD), a 21 aa TM segment and a 303 aa cytoplasmic region. The ECD contains five C2-typeIglikedomains, followed by three FN type III repeats. The ECD of human CDO is 85% aa identical to mouse CDO ECD.CDO is found on muscle precursor and neural progenitor cells of the embryo. It likely promotes muscle differentiation, and contributes to axon guidance andneuronal patterning.
| Product Name: | Human CDO/CDON Recombinant Protein (RPES3555) |
| Product Code: | RPES3555 |
| Size: | 10µg |
| Species: | Human |
| Expressed Host: | Human Cells |
| Synonyms: | Cell adhesion molecule-related/down-regulated by oncogenes, CDON, CDO |
| Accession: | Q4KMG0 |
| Sequence: | Asp26-Pro943 |
| Fusion tag: | C-His |
| Endotoxin: | <1.0 EU per µg as determined by the LAL method. |
| Protein Construction: | Recombinant Human CDO is produced by our Mammalian expression system and the target gene encoding Asp26-Pro943 is expressed with a 6His tag at the C-terminus. |
| Purity: | > 85% as determined by reducing SDS-PAGE. |
| Mol Mass: | 100.4 kDa |
| AP Mol Mass: | 120-135 kDa |
| Formulation: | Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4. |
| Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
| Stability and Storage: | Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
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