Cell Cycle Recombinant Proteins

Human CDKN2C Recombinant Protein (RPES1484)

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SKU:
RPES1484
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Cell Cycle

Description

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Human CDKN2C Recombinant Protein

Cyclin-Dependent Kinase 4 Inhibitor C (CDKN2C) is a member of the INK4 family of cyclin dependent kinase inhibitors. CDKN2C contains 4 ANK repeats and interacts with CDK4 or CDK6. Highest levels of CDKN2C can be found in skeletal muscle, pancreas, and heart. CDKN2C inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB and prevent the activation of the CDK kinases. Studies have been shown the roles of CDKN2C gene in regulating spermatogenesis, as well as in suppressing tumorigenesis.

Product Name:Human CDKN2C Recombinant Protein (RPES1484)
Product Code:RPES1484
Size:10µg
Species:Human
Expressed Host:E.coli
Synonyms:Cyclin-Dependent Kinase 4 Inhibitor C, Cyclin-Dependent Kinase 6 Inhibitor, p18-INK4c, p18-INK6, CDKN2C, CDKN6
Accession:P42773
Sequence:Met 1-Gln168
Fusion tag:N-6His
Endotoxin:<1.0 EU per µg as determined by the LAL method.
Protein Construction:Recombinant Human Cyclin-Dependent Kinase 4 Inhibitor C is produced by our E.coli expression system and the target gene encoding Met1-Gln168 is expressed with a 6His tag at the N-terminus.
Purity:> 95 % as determined by reducing SDS-PAGE.
Mol Mass:20.3 kDa
AP Mol Mass:17 kDa
Formulation:Lyophilized from a 0.2 µm filtered solution of 20mM PB, 150mM NaCl, pH 8.0.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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