Description
system_update_altDatasheet
Antibody Name: | Human CD64 Monoclonal Antibody (Biotin Conjugated) |
Antibody Code: | AGEL0313 |
Size: | 100µg |
Clone: | 10.1 |
Synonyms: | Fc fragment of IgG high affinity Ia/b/c receptor, CD64A/B/C, CD64, Fc gamma RI, FCGR1A/B/C, IGFR 1 |
Host Species: | Mouse |
Species Reactivity: | Human |
Applications: | FC |
Concentration: | 1mg/mL |
Isotype: | IgG1 |
Conjugation: | Biotin |
Applications: | FC |
Recommended Dilution: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10e6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
Storage Buffer: | PBS with 0.05% Proclin300, 1% BSA |
Storage: | Keep as concentrated solution.Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
Gene ID: | 2209 |
Uniprot: | A6NKC4, P12314, Q92637 |
Background: | CD64 is a 72 kD single chain type I glycoprotein also known as FcγRI and FcR I. CD64 is a member of the immunoglobulin superfamily and is expressed on monocytes/macrophages, dendritic cells, and activated granulocytes. The expression can be upregulated by IFN-γ stimulation. CD64 binds IgG immune complex. It plays a role in antigen capture, phagocytosis of IgG/antigen complexes, and antibody-dependent cellular cytotoxicity (ADCC). |