Human CD64 Monoclonal Antibody [10.1](AGEL0312)

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SKU:
AGEL0312
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
10.1
Conjugation:
Unconjugated
Applications:
FC
Applications:
IHC

Description

system_update_altDatasheet
Antibody Name:Human CD64 Monoclonal Antibody
Antibody Code:AGEL0312
Size:100µg
Clone:10.1
Synonyms:Fc fragment of IgG high affinity Ia/b/c receptor, CD64A/B/C, CD64, Fc gamma RI, FCGR1A/B/C, IGFR 1
Host Species:Mouse
Species Reactivity:Human
Applications:FC, IHC
Concentration:1mg/mL
Isotype:IgG1
Conjugation:Unconjugated
Applications:FC, IHC
Recommended Dilution:Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10e6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Storage Buffer:PBS with 0.05% Proclin300
Storage:Keep as concentrated solution.Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Gene ID:2209
Uniprot:A6NKC4, P12314, Q92637
Background:CD64 is a 72 kD single chain type I glycoprotein also known as FcγRI and FcR I. CD64 is a member of the immunoglobulin superfamily and is expressed on monocytes/macrophages, dendritic cells, and activated granulocytes. The expression can be upregulated by IFN-γ stimulation. CD64 binds IgG immune complex. It plays a role in antigen capture, phagocytosis of IgG/antigen complexes, and antibody-dependent cellular cytotoxicity (ADCC).
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