Description
system_update_altDatasheet
Antibody Name: | Human CD58 Monoclonal Antibody |
Antibody Code: | AGEL0271 |
Size: | 100µg |
Clone: | TS2/9.1 |
Synonyms: | Lymphocyte function-associated antigen 3, CD58, Ag3, Surface glycoprotein LFA-3, LFA3 |
Host Species: | Mouse |
Species Reactivity: | Human |
Applications: | FC, IP |
Concentration: | 1mg/mL |
Isotype: | IgG1 |
Conjugation: | Unconjugated |
Applications: | FC, IP |
Recommended Dilution: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10e6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. |
Storage Buffer: | PBS with 0.05% Proclin300 |
Storage: | Keep as concentrated solution.Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
Gene ID: | 965 |
Uniprot: | P19256 |
Background: | CD58, also known as lymphocyte function-associated antigen 3 (LFA-3) is a 45-70 kD cell surface protein that is a member of the immunoglobulin superfamily. Alternative splicing of CD58 gives rise to transmembrane and glycosylphosphatidylinositol (GPI)-anchored forms on cell surface. CD58 is expressed on both hematopoietic and non-hematopoietic cells including B cells, T cells, monocytes, erythrocytes, endothelial cells, epithelial cells, and fibroblasts. High levels are observed on memory T cells and dendritic cells. CD58 expressed on antigen presenting cells and target cells enhances T cell recognition via the binding of it's cognate ligand, CD2, on the T cell surface. |