Description
system_update_altDatasheet
Antibody Name: | Human CD41 Monoclonal Antibody (Alexa Fluor 488 Conjugated) |
Antibody Code: | AGEL0327 |
Size: | 50 Tests |
Clone: | HIP8 |
Synonyms: | Integrin alpha-Iib, ITGA2B, GPalpha Iib, GPIIb, Platelet membrane glycoprotein Iib, CD41, GP2B, ITGAB |
Host Species: | Mouse |
Species Reactivity: | Human |
Applications: | FC |
Concentration: | 5uL |
Isotype: | IgG1 |
Conjugation: | Alexa Fluor 488 |
Applications: | FC |
Recommended Dilution: | Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. The amount of the reagent is suggested to be used 5 uL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
Storage Buffer: | PBS with 0.05% Proclin300, 1% BSA |
Storage: | Keep as concentrated solution.Store at 2-8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
Gene ID: | 3674 |
Uniprot: | P08514 |
Background: | CD41 is a 125/25 kD α subunit of the gpIIb/IIIa (CD41/CD61) complex. CD41 is a heterodimer composed of a heavy chain (gpIIbα) and light chain (gpIIbβ) linked by a single disulfide bond. It is a member of the integrin family primarily expressed on platelets and megakaryocytes. CD41 has been reported to be involved with platelet aggregation and platelet attachment to the ECM. CD41/CD61 complex acts as the receptor for fibrinogen, fibronectin, Von Willebrand factor and thrombin. |
Human peripheral blood lymphocytes are stained with Anti-Human CD41 Monoclonal Antibody (Alexa Fluor 488 Conjugated)(filled gray histogram). Unstained lymphocytes (empty black histogram) are used as control. |